The Eligen® Library
Emisphere has designed and synthesized a library of approximately 4000 delivery agents or carriers. These carriers vary in their chemical structure, solubility, hydrophobicity, electrostatic and other physical and chemical properties. Drugs delivered in clinical studies with Eligen® include unfractionated heparin, low molecular weight heparin, insulin, salmon calcitonin, GLP-1, PYY, gallium, and vitamin B12. In addition, Emisphere has demonstrated successful oral delivery of numerous drug compounds in preclinical studies.